The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 30, 1999

Filed:

Nov. 03, 1997
Applicant:
Inventors:

Carla Anne Haynes, Broadwas, GB;

Elaine Lorimer, Cumbernauld, GB;

Assignee:

Johnson & Johnson Medical, Inc., Arlington, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61F / ;
U.S. Cl.
CPC ...
514 54 ; 424443 ; 514 54 ; 514 55 ; 514 56 ; 514 57 ; 514 58 ; 514 59 ; 514 60 ; 536123 ; 5361231 ;
Abstract

The invention provides a method of preparing water-insoluble polysaccharide sponges, and sponges obtained by means of the method. The method comprises: (a) providing an aqueous solution of a soluble polysaccharide; (b) freezing the solution; (c) treating the frozen solution with a water-miscible organic solvent such as isopropanol to effect solvent exchange for the water in the frozen solution; and (d) drying the resulting polysaccharide material. The organic solvent contains a cross-linking agent such as calcium chloride to render the polysaccharide water-insoluble in the solvent-exchange step (c). The resulting materials are more conformable and less friable than freeze-dried polysaccharide sponges.


Find Patent Forward Citations

Loading…