The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 1999
Filed:
May. 21, 1997
Applicant:
Inventors:
Elsebet Lund, Madison, WI (US);
James E Dahlberg, Madison, WI (US);
Lu-Shiun Her, Madison, WI (US);
Yan Cheng, San Francisco, CA (US);
Christian Grimm, Naenikon/Greifense, CH;
Assignee:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12Q / ; C12N / ; C07H / ;
U.S. Cl.
CPC ...
435-5 ; 435-6 ; 435-71 ; 435-72 ; 435325 ; 435375 ; 435455 ; 536 231 ; 536 2372 ; 536 241 ;
Abstract
A method of inhibiting transport of nucleic acids between the nucleus and cytoplasm of a cell is disclosed. In one embodiment, this method comprises the step of exposing a cell to a sufficient amount of vesicular stomatitis virus M protein such that the transport of RNA and protein through the nuclear envelope of the cell is impeded. A chimeric RNA capable of nuclear export is also disclosed.