The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 23, 1999
Filed:
Dec. 29, 1995
Applicant:
Inventors:
Murty N Arimilli, Fremont, CA (US);
Norbert W Bischofberger, San Carlos, CA (US);
Robert J Jones, Millbrae, CA (US);
William A Lee, Los Altos, CA (US);
Ernest J Prisbe, Los Altos, CA (US);
Assignee:
Gilead Sciences, Inc., Foster City, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07F / ; A61K / ;
U.S. Cl.
CPC ...
544243 ; 544179 ; 544182 ; 544195 ; 514 79 ; 514 84 ; 514 86 ;
Abstract
Nucleotide phosphonate esters characterized by the presence of an ester linked group which is bonded to the phosphorus atom of phosphonate nucleotide analogs are disclosed. The analogs comprise an ester bond that is hydrolyzed in vivo to yield a corresponding phosphonate nucleotide analog. Methods and intermediates for their synthesis and use are described.