The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 09, 1999

Filed:

May. 13, 1992
Applicant:
Inventors:

Bertil Aberg, Stockholm, SE;

Andras Simoncsits, Stockholm, SE;

Miklos Kalman, Szeged, HU;

Imre Cserpan, Szeged, HU;

Gyorgy Bajszar, Szeged, HU;

Assignees:

Skandigen AB, Stockholm, SE;

MTA Szegedi Biologiai Kozpontja, Szeged, HU;

Vepex Contractor Ltd., Budapest, HU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C07H / ;
U.S. Cl.
CPC ...
435 691 ; 4351723 ; 43525233 ; 4352542 ; 43525421 ; 4353201 ; 536 231 ; 536 235 ;
Abstract

A structural gene coding for authentic human serum albumin, --optionally supplemented by an upstream triplet coding for methionine and optionally extended by a synthetic prepro.sup.x -leader-coding sequence--, wherein the codons of the nucleotide sequence have been selected with regard to a non-human host, e.g. yeast, chosen for expression of authentic human serum albumin, is disclosed. Additionally there is disclosed a method of producing said gene. There are also disclosed a recombinant DNA molecule comprising said strucural gene inserted into a vector, and a host transformed with said recombinant DNA molecule. Furthermore there are disclosed a method of producing authentic human serum albumin, an authentic human serum albumin resulting from said method, and a pharmaceutical composition comprising said resulting human serum albumin.


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