The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 09, 1999

Filed:

Jul. 23, 1996
Applicant:
Inventors:

Burkhard Raguse, St. Ives, AU;

Ronald John Pace, Homebush, AU;

Lionel George King, Marafield, AU;

Vijoleta Licija Braach-Makavytie, Dulwich Hill, AU;

Bruce Cornell, Neutral Bay, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ;
U.S. Cl.
CPC ...
435-4 ; 204400 ; 204403 ; 204415 ; 204416 ; 204418 ; 422 8201 ; 422 8203 ; 4352871 ; 435817 ; 436 71 ; 436518 ; 436528 ; 436806 ; 427-211 ; 427-213 ; 427 58 ; 427337 ; 427338 ;
Abstract

Electrode membrane combinations for use in biosensors to detect analytes in a sample and methods for making and storing same are disclosed. In one aspect, a method is provided for producing a first layer electrode membrane comprising: (1) Forming a solution containing Linker Lipid A, the disulfide of mercaptoacetic acid (MAAD) or similar molecule, linker Gramicidin B, membrane spanning lipid C (MSL-C) and membrane spanning lipid D (MSL-D) or other suitable linker molecules and other ion channel combinations; (2) Contacting an electrode containing a clean gold surface with the solution, the disulfide containing components in the solution thus adsorbing onto the gold surface of the electrode; (3) Rinsing the electrode with a suitable organic solvent; and (4) Removing the excess organic solvent used for rinsing.


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