The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 1999
Filed:
Dec. 24, 1997
Applicant:
Inventor:
Kenneth E Anderson, Allegan, MI (US);
Assignee:
Wyckoff Chemical Company, Inc., South Haven, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ;
U.S. Cl.
CPC ...
564425 ; 564438 ;
Abstract
A process for the isolation and purification of (RR,SS)-2-�(dimethylamino)methyl!-1-(3-methoxyphenyl)cyclohexanol and its salts from a Grignard reaction mixture which includes the (RR,SS) isomer, the (RS,SR) isomer and Grignard reaction side products. An aqueous solution of HBr is added to the reaction mixture to effect the selective precipitation of the (RR,SS) hydrobromide isomer from the mixture while the (RS,SR) isomer remains in solution. The precipitated (RR,SS)-2-�(dimethylamino)methyl!-1-(3-methoxyphenyl)cyclohexanol hydrobromide is converted to (RR,SS)-2-�(dimethylamino)methyl!-1-(3-methoxyphenyl)cyclohexanol hydrochloride.