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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5877006 B1

PDFFull Text
Date of Patent:
Mar. 02, 1999

Filed:

May. 17, 1995

Dnas encoding chimeric immunoglobulin light or heavy chains and

Applicant:
Inventors:

Barry S Coller, Dix Hills, NY (US);

David M Knight, Paoli, PA (US);

Assignees:

Centocor, Inc., Malvern, PA (US);

The Research Foundation of State of New York, Stony Brook, NY (US);

Attorney:

Hamilton, Brook, Smith & Reynolds, P.C.

Primary Examiner:

Lila Feisee

Assistant Examiner:

Phillip Gambel

Int. Cl.
CPC ...
C07H / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
4352523 ; 536 234 ; 536 235 ; 536 2353 ; 4353201 ; 435326 ; 435328 ; 435332 ; 435334 ; 435337 ; 435343 ;
Abstract

Platelet-specific, chimeric immunoglobulin and immunoglobulin fragments are described. The chimeric molecules are made up of a nonhuman antigen binding region and a human constant region. Preferred immunoglobulins are specific for glycoprotein IIb/IIIa receptor in its complexed form; they block ligand binding to the receptor and prevent platelet aggregation. The immunoglobulins are useful in anti-thrombotic therapy when administered alone or in conjunction with thrombolytic agents, as well as in thrombus imaging.

Find Patent Forward Citations

Coller, Barry. (1999). Dnas encoding chimeric immunoglobulin light or heavy chains and (U.S. Patent No. 5877006). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5877006

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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