The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 1999
Filed:
Nov. 16, 1995
Douglas C Knipple, Geneva, NY (US);
Wendell L Roelofs, Geneva, NY (US);
Stuart J Miller, Geneva, NY (US);
Cornell Research Foundation, Inc., Ithaca, NY (US);
Abstract
The present invention is directed to isolated membrane-associated acyl-CoA desaturases expressed in the pheromone gland of an insect and, in particular, the .DELTA.11 desaturase of Trichoplusia ni. The present invention further relates to an isolated DNA molecule encoding the T. ni .DELTA.11 desaturase, expression vectors comprising the DNA molecule, and host cells comprising the expression vectors. Methods for isolating DNA sequences of homologous acyl-CoA desaturases expressed in the pheromone glands of insects are provided. The use of these acyl-CoA desaturases, DNA molecules, expression vectors, and host cells to produce an unsaturated fatty acyl-CoA product from a saturated or unsaturated fatty acyl-CoA reactant is also disclosed. The unsaturated fatty acyl-CoA products are useful as pheromones or as pheromone precursors as well as in the preparation of organic molecules, such as drugs.