The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 1999
Filed:
May. 24, 1995
Keith E Dionne, Rehoboth, MA (US);
Dwaine F Emerich, Providence, RI (US);
Diane Hoffman, Cambridge, MA (US);
Paul R Sanberg, Spring Hill, FL (US);
Lisa Christenson, New Haven, CT (US);
Orion D Hegre, Green Valley, AZ (US);
David W Scharp, St. Louis, MO (US);
Paul E Lacy, Webster Grove, MO (US);
Patrick Aebischer, Lutry, CH;
Alfred V Vasoohcellos, Cranston, RI (US);
Michael J Lysaght, E. Greenwich, RI (US);
Frank T Gentile, Warwich, RI (US);
Abstract
A method of forming an implantable and retrievable immunoisolatory vehicles is disclosed, the method comprising the steps of first forming a core comprising a volume of at least 1 .mu.l and at least 10.sup.4 cells capable of providing a biologically active product or metabolic or immunologic function, said cells being dispersed in a biocompatible hydrogel or extracellular matrix, and then forming around the core a surrounding external biocompatible thermoplastic or hydrogel jacket free of said cells projecting externally thereof, said jacket having molecular weight cutoff permitting passage of molecules to and from the core through said jacket to provide said biologically active product or function.