The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 1999
Filed:
Mar. 08, 1995
Applicant:
Inventors:
James J Mond, Jerusalem, IL;
Clifford M Snapper, Potomac, MD (US);
Assignee:
Henry M. Jackson Foundation for the Advancement of Military Medicine, Rockville, MD (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
42419511 ; 4241841 ; 4241931 ; 4241941 ; 4242781 ; 424 852 ; 424 854 ; 42419711 ;
Abstract
The invention describes compositions and methods for optimizing IgA class switching in B cells. The compositions comprise a multivalent antigen receptor crosslinker, CD40 ligand or lipopolysaccharide, and the cytokines TGF-.beta., IL-4, and either IL-5 or IL-2. Methods of using the compositions are also described.