The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 1999

Filed:

Sep. 23, 1997
Applicant:
Inventor:

Jeffrey N Weiser, Merion, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12Q / ; C12Q / ;
U.S. Cl.
CPC ...
435 29 ; 435 17 ; 435-4 ; 4352534 ; 435885 ; 435851 ; 435 32 ;
Abstract

The invention relates to a method of identifying a compound capable of disrupting the addition of choline onto a bacterial cell surface component comprising incubating a sample of bacteria in a solution containing choline in the presence or absence of a test compound, and assessing the effect of the test compound on the addition of choline onto the bacterial cell surface component, wherein a lower level of choline on the cell surface component in the presence of the test compound, compared with the level of choline on the cell surface component in the absence of the test compound, is an indication that the test compound inhibits the addition of choline onto the cell surface component.


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