The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 1999
Filed:
Jan. 27, 1997
Applicant:
Inventors:
Michael Yarus, Boulder, CO (US);
Mali Illangasekare, Boulder, CO (US);
Assignee:
NeXstar Pharmaceuticals, Inc., Boulder, CO (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; C12P / ; C07H / ;
U.S. Cl.
CPC ...
435-6 ; 435 911 ; 435 912 ; 435 9151 ; 536 221 ;
Abstract
The instant invention provides a method for identifying and preparing nucleic acid ligands capable of facilitating aminoacyl-RNA synthesis. The nucleic acid ligands are identified and produced by exposure of candidate nucleic sequences to a reactant under conditions conducive to reaction, wherein nucleic acid sequences having facilitative activity are able to facilitate or enhance a reaction between the reactant molecule and nucleic acid sequence. Included in the invention are specific RNA ligands capable of facilitating aminoacyl-RNA synthesis identified by the SELEX method.