The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 1999
Filed:
Jul. 11, 1995
Tomiko Kashiwakuma, Itabashi-ku, JP;
Shintaro Yagi, Iruma-gun, JP;
Akira Hasegawa, Sakado, JP;
Tadahiro Kajita, Nishinomiya, JP;
Yohsuke Ohta, Kobe, JP;
Hiroyuki Mori, Osaka, JP;
The Tokyo Metropolitan Institute of Medical Science, Tokyo, JP;
International Reagent Corporation, Hyogo-ken, JP;
Tonen Corporation, Tokyo, JP;
Abstract
This invention concerns a monoclonal antibody having binding specificity for an antigenic determinant site on core structural protein from Non-A,Non-B hepatitis virus (NANBV); a hybridoma cell line capable of producing the monoclonal antibody; a process for the preparation of the monoclonal antibody; an immunoassay of NANBV-related antigens by use of the monoclonal antibody; and a test kit for use in the immunoassay. The preferred monoclonal antibody is 5E3, 5F11, 515S or 1080S. The monoclonal antibody can specifically recognize the NANBV core structural protein in sera from patients with Non-A,Non-B hepatitis thereby being served extensively as an antibody in various immunological reagents for definitive diagnosis of Non-A, Non-B hepatitis.