The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 1999
Filed:
Oct. 08, 1997
Judy A Magruder, Mt. View, CA (US);
James B Eckenhoff, deceased, late of Los Altos, CA (US);
Richard Cortese, Los Gatos, CA (US);
Jeremy C Wright, Los Altos, CA (US);
John R Peery, Stanford, CA (US);
James B Pike, St. Louis, MO (US);
Urano A Robinson, St. Louis, MO (US);
Jonathan P Smith, St. Louis, MO (US);
Lyle E Ziemann, Chesterfield, MO (US);
ALZA Corporation, Palo Alto, CA (US);
Abstract
A delivery system (10) is disclosed for delivering a fluid-sensitive beneficial agent (7) such as a somatotropin, or an analogue or derivative thereof, to an animal such as a bovine. The delivery system comprises a wall that surrounds an internal compartment, said wall comprising a first wall section that limits the passage of fluid into the system and a second wall section that permits the passage of fluid into the system. An exit passageway is provided for delivering the beneficial agent an interior compartment (18) to the animal. The exit passageway is sealed with a wax seal (30) which is expelled through the passageway (13) as the internal pressure within the device (10) reaches a predetermined 'bursting' pressure. The passageway (13) is preferably sized to compensate for slight variations in the efflux of the beneficial agent and to maintaining a sufficient volumetric outflow rate of beneficial agent in order to minimize influx of biological fluids from the external environment back into the device once the seal (30) is expelled.