The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 1999

Filed:

Aug. 21, 1996
Applicant:
Inventors:

Craig E Whitfill, Apex, NC (US);

John A Thoma, Fayetteville, AR (US);

Tommy L Fredericksen, Ashford, CT (US);

Julius K Tyczkowski, Cary, NC (US);

J Paul Thaxton, Jr, Brandon, MS (US);

Assignees:

Embrex, Inc, Research Triangle Park, NC (US);

The University of Arkansas, Fayetteville, AR (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
4242151 ; 5303871 ; 5303883 ; 5303894 ; 4352351 ; 435948 ;
Abstract

A method of producing active immunity against a viral disease in an animal subject comprises administering to the subject a vaccine conjugate consisting essentially of a live virus and a neutralizing factor bound to the live virus. The neutralizing factor is selected from the group consisting of antibodies and antibody fragments. The live virus is one capable of producing disease in the subject, and the antibody or antibody fragment is one capable of neutralizing the live virus. Preferred subjects are birds, a preferred virus is Infectious Bursal Disease Virus, and a preferred route of administration to birds is by in ovo administration.


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