The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 1999

Filed:

Mar. 13, 1997
Applicant:
Inventors:

Toshio Kudo, Sendai, JP;

Shuichi Hiyamuta, Sodegaura, JP;

Toshiyuki Tanedani, Sodegaura, JP;

Akihiko Kadota, Sodegaura, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; C07K / ;
U.S. Cl.
CPC ...
435-723 ; 4353913 ; 53038815 ; 5303888 ; 5303913 ; 5303917 ; 436 64 ;
Abstract

A method for producing a human lymphocyte producing an antibody specific to a desired antigen, a method for producing a monoclonal antibody, as well as monoclonal antibodies produced by the method, are described. The present invention provides a method for producing a human lymphocyte producing an antibody comprising, in the order mentioned, the steps of: transplanting human lymphocytes into an immunodeficient animal so that the human lymphocytes take in the animal body; immunizing the animal with a desired antigen so as to generate human lymphocytes producing an antibody specific to the antigen; and recovering the human lymphocytes producing the antibody from the animal. The present invention also provides a method for producing a monoclonal antibody comprising, in the order mentioned, the steps of: immortalizing the human lymphocytes producing the antibody which were obtained by the above-mentioned method of the present invention; cloning the obtained immortalized human-derived lymphocytes producing the antibody; and recovering a monoclonal antibody specific to the desired antigen from the cloned immortalized human-derived lymphocytes.


Find Patent Forward Citations

Kudo, Toshio. (1999). Methods for producing human lymphocytes and human monoclonal antibodies, (U.S. Patent No. 5869268). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5869268

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