The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 1999
Filed:
May. 24, 1995
Keith E Dionne, Rehoboth, MA (US);
Dwaine F Emerich, Providence, RI (US);
Diane Hoffman, Cambridge, MA (US);
Paul R Sanberg, Spring Hill, FL (US);
Lisa Christenson, New Haven, CT (US);
Orion D Hegre, Green Valley, AZ (US);
David W Scharp, St. Louis, MO (US);
Paul E Lacy, Webster Grove, MO (US);
Patrick Aebischer, Lutry, CH;
Alfred V Vasconcellos, Cranston, RI (US);
Michael J Lysaght, Greenwich, RI (US);
Frank T Gentile, Warwich, RI (US);
Abstract
A method for treating diabetes in a patient comprising subcutaneously implanting in the patient at least one immunoisolatory vehicle comprising a core comprising a volume of at least 1 .mu.l and at least about 10.sup.4 living cells which secrete insulin, said cells being dispersed in a biocompatible matrix comprising a hydrogel or extracellular matrix components, and a surrounding external jacket of a biocompatible thermoplastic or hydrogel free of said cells projecting externally thereof, said jacket being permselective and immunoisolatory, said jacket having a molecular weight cutoff permitting passage of molecules between the patient and core through said jacket wherein the insulin is released from the immunoisolatory vehicle into the patient's body to treat diabetes.