The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 1999
Filed:
Nov. 13, 1996
Applicant:
Inventors:
Charles J Link, Jr, Clive, IA (US);
John P Levy, West Des Moines, IA (US);
Assignee:
Human Gene Therapy Research Institute, Des Moines, IA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ; A01N / ; A61K / ; C12N / ;
U.S. Cl.
CPC ...
424 937 ; 514 44 ; 4242771 ; 424 9321 ; 4352402 ; 4353201 ;
Abstract
The invention discloses methods and compositions for killing tumor cells in animals. Through transfer techniques, cancer cells are engineered to express an epitope which is targeted by natural antibodies causing complement destruction of transformed tumor cells that is typically associated with hyperacute xenograft rejection.