The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 1999

Filed:

Mar. 14, 1996
Applicant:
Inventors:

Thomas Schalkhammer, Kasten, AT;

Fritz Pittner, Wien, AT;

Alfred Leitner, Graz, AT;

Franz Aussenegg, Graz, AT;

Harald Brunner, Graz, AT;

Assignee:

AVL Medical Instruments AG, Schaffhausen, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
436525 ; 422 57 ; 422 8205 ; 422 8208 ; 422 8211 ; 435-6 ; 4352871 ; 4352872 ; 4352879 ; 4352887 ; 435808 ; 436518 ; 436524 ; 436527 ; 436164 ; 436165 ; 436172 ; 436805 ; 436807 ; 385 12 ; 385129 ; 385131 ;
Abstract

An optochemical fluorescence sensor with a biorecognitive layer for measuring the concentration of one or more analytes in a sample is provided with at least one island layer which is applied on a sensor substrate. The islands of the island layer are in the form of electrically-conductive material and have a diameter of less than 300 nm, the biorecognitive layer being directly applied on the island layer or bound via a spacer film. In addition, an analyte-specific fluorescent compound is provided which may be added to the sample or is provided in the sensor itself. The biorecognitive layer can bind the analyte to be measured directly or by means of analyte-binding molecules, the originally low quantum yield of the fluorescent compound increasing strongly in the vicinity of the island layer.


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