The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 1999
Filed:
Sep. 16, 1996
Martin G Meder, Hightstown, NJ (US);
Other;
Abstract
The invention is a roller bottle having a cross-section that is substantially a non-circular closed curve of constant width, wherein said curve is preferably a Reuleaux triangle or a Reuleaux triangle with rounded corners and the use of the roller bottle for cell culture. This provides several benefits: 1) a larger surface area per unit volume than a circular cross-section, promoting growth of anchorage dependant cells while maintaining an easily harvested and cleaned smooth wall. 2) a translational motion in addition to the usual circular motion, which is expected to enhance gas exchange, especially at the cap, which normally sits on an axis and has low angular velocity. 3) greater agitation of the growth medium inside the bottle, without the need for difficult to manufacture inserts or internal baffles.