The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 1999

Filed:

Aug. 26, 1996
Applicant:
Inventors:

Aleksandr K Rabinovich, La Jolla, CA (US);

Dale S Dhanoa, Del Mar, CA (US);

David R Luthin, San Diego, CA (US);

Richard A Bychowski, Cardiff, CA (US);

Dilip R Bhumralkar, San Diego, CA (US);

Assignee:

Alanex Corporation, San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
514250 ; 544245 ;
Abstract

Benzo(e)perimidine-4-carboxamide derivatives of general structural formula I ##STR1## (where R.sub.a, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 are as defined in the specification) have activity for receptors of corticotropin releasing factor (CRF). The compounds are useful in treating stress-related diseases, cardiovascular, neurological and psychiatric disorders including anxiety, depression, eating disorders, anorexia nervosa, superanuclear palsy, irritable bowel syndrome, gastrointestinal diseases, immune suppression, inflammatory disorders, drug and alcohol withdrawal symptoms, drug addiction, Alzheimer's disease or fertility disorders.


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