The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 1999
Filed:
Jun. 06, 1996
Applicant:
Inventors:
Christopher John Stanley, Huntingdon, GB;
Henrik Orum, Vaerlose, DK;
Mikkell Jorgensen, Glostrup, DK;
Ole Basboll, Birkerod, DK;
Assignee:
PNA Diagnostics A/S, Copenhagen, DK;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C07H / ; C12N / ;
U.S. Cl.
CPC ...
435-6 ; 435 912 ; 435 911 ; 536 2532 ; 536 173 ; 935 77 ; 935 78 ;
Abstract
A selected region of a nucleic acid is protected from attach by nuclease by completing to the nucleic acid a nucleic acid analogue of the PNA type. The surviving sequence may be detected in an assay, optionally after amplification. A PCR reaction may be sterilized and its product assayed by protecting a characterizing region of the product by PNA hybridization followed by nuclease degradation of unprotected nucleic acid.