The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 1999

Filed:

Nov. 21, 1996
Applicant:
Inventors:

Takaaki Nishioka, Nabari, JP;

Kenji Kuratani, Shiga, JP;

Haruo Kanasaki, Shiga, JP;

Helmut Luchtenberg, Niederkassel, DE;

Ulrich Tenter, Solingen, DE;

Andreas Ohm, Neuss, DE;

Assignee:

Bayer Aktiengesellschaft, Leverkusen, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
424480 ; 424482 ; 424474 ;
Abstract

This invention provides a long-lasting release solid nifedipine preparation which exhibits clinically sufficient effect when administered once per day. A press coated tablet whose core and shell each contains nifedipine, the dissolution rate of nifedipine from said tablet being (a) in the dissolution test using a sinker according to method 2 of the dissolution test method as prescribed by the Pharmacopoeia of Japan, after 2 hours 10-40% after 4 hours 30-65% after 6 hours at least 55%, and (b) in the dissolution test according to the disintegration test method as prescribed by the Pharmacopoeia of Japan, after 3 hours 20-45% after 4 hours 30-65%.


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