The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 19, 1999
Filed:
Dec. 24, 1996
Hyun Su Kim, Seoul, KR;
Wan Je Park, Suwon, KR;
Wang Don Yoo, Seongnam, KR;
Kap Soo Noh, Seoul, KR;
Dong Eok Lee, Seoul, KR;
Suk Hoon Ha, Seoul, KR;
Ree An Yoo, Kwachun, KR;
Nam Joong Lee, Seoul, KR;
Yang Je Cho, Seoul, KR;
Sun Pyo Hong, Seoul, KR;
Je Hak Kim, Suwon, KR;
Dal Hyun Kim, Suwon, KR;
Young Gi Kim, Seoul, KR;
Cheil Jedang Corporation, , KR;
Abstract
The present invention relates to a vaccine prepared from an attenuated Pseudomonas aeruginosa strains which are obtained by isolating Pseudomonas aeruginosa in a pure state according to the Fisher-Devlin immunotype and then repeatedly purifying the isolated strain, particularly CFCPA 10142 (KCCM 10029), CFCPA 20215 (KCCM 10030), CFCPA 30720 (KCCM 10031), CFCPA 40057 (KCCM 10032), CFCPA 50243 (KCCM 10033), CFCPA 60534 (KCCM 10034) and CFCPA 70018 (KCCM 10035) strains. In addition, the present invention relates to a process for preparing the vaccine for immunization against Pseudomonas aeruginosa infection which contains cell wall proteins having molecular weights ranging from 10,000 to 100,000. The cell wall protein component of the attenuated strain is non-pathogenic and safe, and exhibits excellent antibody formation capacity and is useful for preparation of a vaccine and therapeutic agent. The cell wall proteins exhibit an excellent cross-protective efficacy for various Pseudomonas aeruginosa strains and a superior antibody inducing property.