The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 1999

Filed:

May. 08, 1995
Applicant:
Inventors:

Robert J Hawley, Newton, MA (US);

Rodney L Monroy, Rockport, MA (US);

Margaret D Rosa, Winchester, MA (US);

Bernice Z Schacter, Madison, CT (US);

Paul D Ronath, Boston, MA (US);

Assignee:

BioTransplant, Inc., Charlestown, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A01N / ;
U.S. Cl.
CPC ...
514-2 ; 424 932 ; 424 931 ; 424 851 ; 4352402 ;
Abstract

A method of enhancing tolerance of a porcine transplant in a xenogeneic recipient by administering porcine bone marrow cells to the recipient and of enhancing proliferation and engraftment of the porcine bone marrow cells by exposing said cells to at least one substantially pure porcine cytokine and porcine cytokines that are substantially free of other porcine proteins and preferentially enhance the proliferation and engraftment of porcine bone marrow cells in the presence of bone marrow cells of other species. Protein and DNA sequence(s) for such porcine cytokines.


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