The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 1999
Filed:
Feb. 28, 1997
David M Soderlund, Geneva, NY (US);
Patricia J Ingles, Geneva, NY (US);
Cornell Research Foundation, Inc., Ithaca, NY (US);
Abstract
The present invention is directed to isolated nucleic acid molecules encoding a voltage-sensitive sodium channel (VSSC) of an insect having a mutation therein which renders the sodium channel permeable to calcium, as well as to the isolated calcium permeable voltage-sensitive sodium channels encoded thereby. Nucleic acid molecules encoding calcium permeable VSSCs of Musca domestica, Drosophila melanogaster, and Heliothis virescens are specifically provided. These calcium permeable channels can be used to monitor the function of the channel by monitoring calcium transport through the sodium channel, and for screening chemical agents for the ability of the chemical agent to modify sodium channel function, again by monitoring calcium transport through the channel.