The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 1999
Filed:
Jun. 07, 1995
Edward F Nemeth, Salt Lake City, UT (US);
Edward M Brown, Milton, MA (US);
Steven C Hebert, Wellesley, MA (US);
James E Garrett, Jr, Salt Lake City, UT (US);
Bradford C Van Wagenen, Salt Lake City, UT (US);
Manuel F Balandrin, Sandy, UT (US);
Eric G Del Mar, Salt Lake City, UT (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
NPS Pharmaceuticals, Inc., Salt Lake City, UT (US);
Abstract
The present invention relates to the different roles inorganic ion receptors have in cellular and body processes. The present invention features: (1) molecules which can modulate one or more inorganic ion receptor activities, preferably the molecule can mimic or block an effect of an extracellular ion on a cell having an inorganic ion receptor, more preferably the extracellular ion is Ca.sup.2+ and the effect is on a cell having a calcium receptor; (2) inorganic ion receptor proteins and fragments thereof, preferably calcium receptor proteins and fragments thereof; (3) nucleic acids encoding inorganic ion receptor proteins and fragments thereof, preferably calcium receptor proteins and fragments thereof; (4) antibodies and fragments thereof, targeted to inorganic ion receptor proteins, preferably calcium receptor protein; and (5) uses of such molecules, proteins, nucleic acids and antibodies.