The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 1999

Filed:

May. 24, 1995
Applicant:
Inventors:

Joseph Schlessinger, New York, NY (US);

Jan M Sap, New York, NY (US);

Axel Ullrich, Munchen, DE;

Wolfgang Vogel, Germering, DE;

Miriam Fuchs, Starnberg, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ;
U.S. Cl.
CPC ...
435196 ; 435 691 ; 435 697 ; 536 235 ; 530350 ;
Abstract

A novel receptor-type protein tyrosine phosphatase-.kappa. (RPTP.kappa.) protein or glycoprotein and the DNA coding therefor is expressed in a wide variety of mammalian tissues. The RPTP.kappa. protein or glycoprotein may be produced by recombinant means. Antibodies to the protein, methods for measuring the quantity of the protein, methods for screening compounds, such as drugs, which can bind to the protein and inhibit or stimulate their enzymatic activity, are provided. Further, methods for inhibiting homophilic binding of Type II RPTP, especially RPTP.kappa. molecules are provided.


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