The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 1999

Filed:

Jul. 02, 1997
Applicant:
Inventors:

Karel J Lambert, San Diego, CA (US);

Sheila Benay Podell, San Diego, CA (US);

Edward G Jablonski, Escondido, CA (US);

Carl Hulle, San Diego, CA (US);

Kenneth Hamilton, Cardiff, CA (US);

Rolf Lohrmann, La Jolla, CA (US);

Assignee:

Molecular Biosystems, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B / ;
U.S. Cl.
CPC ...
424-952 ;
Abstract

Elastic protein microspheres, filled with water insoluble gases, have been produced by ultrasound and mechanical cavitation without the present of oxygen. The microspheres are highly echogenic. The microspheres exhibit greatly enhanced static pressure stability, up to 40 psig. The microspheres are resistant to coalescence and to expansion due to differential gas diffusion. The microspheres are resistant to collapse when suspended in a gas-depleted aqueous solution.


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