The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 1998

Filed:

Jul. 28, 1997
Applicant:
Inventors:

Hermann Oppermann, Medway, MA (US);

Engin Ozkaynak, Milford, MA (US);

Thangavel Kuberasampath, Medway, MA (US);

David C Rueger, Hopkinton, MA (US);

Roy H Pang, Etna, NH (US);

Charles M Cohen, Medway, MA (US);

Assignee:

Creative BioMolecules, Inc., Boston, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
435353 ; 435325 ; 435366 ; 530350 ; 530399 ;
Abstract

Disclosed are (1) nucleic acid and amino acid sequences for a novel morphogenic protein; (2) methods for producing and expressing the protein in a biologically active form; and (3) methods for utilizing the protein to induce tissue morphogenesis in a mammal, including methods for increasing a progenitor cell population in a mammal, methods for stimulating progenitor cells to differentiate and maintain their differentiated phenotype in vivo or in vitro, methods for inducing tissue-specific growth in vivo and methods for the replacement of diseased or damaged tissue in vivo.


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