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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5852173 B1

PDFFull Text
Date of Patent:
Dec. 22, 1998

Filed:

Sep. 26, 1995

Tnf receptor death ligand proteins and inhibitors of ligand binding

Applicant:
Inventors:

Lih-Ling Lin, Concord, MA (US);

Jennifer Chen, Chestnut Hill, MA (US);

Andrea R Schievella, Winchester, MA (US);

James Graham, Somerville, MA (US);

Assignee:

Genetics Institute, Inc., Cambridge, MA (US);

Attorneys:

Sprunger; Suzanne A.

Brown; Scott A.

DesRosier; Thomas J.

Primary Examiner:

Stephen Walsh

Assistant Examiner:

Claire M Kaufman

Int. Cl.
CPC ...
C07K / ; C07K / ; C12N / ;
U.S. Cl.
CPC ...
530350 ; 514-2 ; 514 12 ; 435 691 ; 435325 ; 530300 ; 530351 ;
Abstract

Novel TNF receptor death domain ('TNF-R1-DD') ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.

Find Patent Forward Citations

Lin, Lih-Ling. (1998). Tnf receptor death ligand proteins and inhibitors of ligand binding (U.S. Patent No. 5852173). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5852173

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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