The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 1998
Filed:
Dec. 14, 1995
Applicant:
Inventors:
Imre Kovesdi, Rockville, MD (US);
Douglas E Brough, Olney, MD (US);
Duncan L McVey, Derwood, MD (US);
Joseph T Bruder, Gaithersburg, MD (US);
Alena Lizonova, Rockville, MD (US);
Assignee:
GenVec, Inc., Rockville, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 9141 ; 4353201 ; 435325 ; 435366 ; 536 242 ;
Abstract
The present invention provides multiply replication deficient adenoviral vectors having a spacer in at least one replication deficient adenoviral region, as well as complementing cell lines therefor. Also provided are means of constructing the multiply replication deficient adenoviral vectors and methods of use thereof, e.g., in gene therapy.