The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 1998

Filed:

Dec. 01, 1993
Applicant:
Inventors:

Ruth Anne McAdam, Bronx, NY (US);

Jeremy Watson Dale, Guildford, GB;

Zainul Fadziruddin Zainuddin, Penang, MY;

David Catty, Birmingham, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ;
U.S. Cl.
CPC ...
435-6 ; 536 237 ;
Abstract

The invention provides nucleotide probes, kits and methods for the detection and differentiation of Mycobacteria. The gene probes, kits and methods are useful for the diagnosis of tuberculosis and/or for epidemiological study tools for investigating the progress of infections caused by Mycobacteria. The gene probes as provided comprise part or all of nucleotide sequences provided in the soecification or an allele or a derivative of the nucleotide sequences. The gene probes can distinguish between M.tuberculosis, M.bovis and BCG as well as being able to distinguish between different strains of M.tuberculosis. The probes do not show significant hybridisation to nucleic acids from M.paratuberculosis, M.intracellulare, M.scrofulaceum, M.phlei, M.fortuitum, M.kansasii, M.avium, M.malnioense. M.flavescens, M.gordonae and M.chelonei.


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