The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 1998

Filed:

Mar. 14, 1996
Applicant:
Inventors:

Raghunath Anant Mashelkar, Maharashtra, IN;

Mohan Gopalkrishna Kulkarni, Maharashtra, IN;

Rohini Nitin Karmalkar, Maharashtra, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F / ; A61K / ;
U.S. Cl.
CPC ...
424426 ; 424457 ; 424484 ; 424486 ;
Abstract

The present invention provides a polymer for the controlled release of a pendent chain linked active ingredient, and a process for the preparation of such a polymer for the controlled release of an active ingredient in response to pH. The process involves selecting a vinyl monomer to which the active ingredient molecule is covalently linked through a pendent group, and selecting monomers bearing catalytic groups. The active ingredient-bearing monomer and the catalytic group-containing monomer are brought in juxtaposition either by complexation or molecular imprinting, and then polymerized with a hydrophilic monomer and crosslinker under an inert atmosphere with a suitable polymerization initiator.


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