The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 1998
Filed:
Jun. 06, 1995
Applicant:
Inventors:
Nicholas P Restifo, Washington, DC (US);
Steven A Rosenberg, Bethesda, MD (US);
Jack R Bennink, Olney, MD (US);
Igor Bacik, Rockville, MD (US);
Jonathan W Yewdell, Silver Springs, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C12N / ; C07H / ;
U.S. Cl.
CPC ...
4241921 ; 4242341 ; 4242651 ; 4242771 ; 4353201 ; 536 234 ; 536 241 ;
Abstract
Immunogenic chimeric proteins comprising an endoplasmic reticulum signal sequence and at least one other peptide are disclosed. The invention relates to the design of vaccinia virus constructs capable of directing host organism synthesis of immunogenic chimeric proteins which can be used as immunogens, as vaccines, or in methods of treatment for cancer, infectious diseases, or autoimmune diseases.