The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 1998
Filed:
Jun. 25, 1993
Mordecai P Blaustein, Baltimore, MD (US);
John M Hamlyn, Baltimore, MD (US);
Douglas W Harris, Portage, MI (US);
James H Ludens, Portage, MI (US);
William Rodney Mathews, Plainwell, MI (US);
Jed F Fisher, Three Rivers, MI (US);
Frederic Mandel, Vicksburg, MI (US);
Donald W DuCharme, Paw Paw, MI (US);
University of Maryland, Baltimore, Baltimore, MD (US);
Abstract
Methods for diagnosing pre-hypertension, hypertension, congestive cardiomyopathy, renal failure, salt-sensitivity and adenomas and endocrine cell hyperplasias are disclosed. Also disclosed are methods for monitoring hypertension therapy, congestive cardiomyopathy therapy, renal failure therapy and adenoma and endocrine cell hyperplasia therapy. These methods involve using an antibody having binding specificity to ouabain to immunologically measure the level of human ouabain in body fluid or tissue of a subject. Additionally, methods for treating a hypertensive subject by inducing passive or active immunity to human ouabain in the subject are disclosed, along with an antibody having binding specificity for ouabain.