The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 1998
Filed:
Nov. 02, 1995
Applicant:
Inventors:
R John Collier, Wellesley Hills, MA (US);
David Eisenberg, Los Angeles, CA (US);
Haian Fu, Allston, MA (US);
Seunghyon Choe, Reseda, CA (US);
Assignees:
The Regents of the University of California, Oakland, CA (US);
The President and Fellows of Harvard College, Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ;
U.S. Cl.
CPC ...
435 691 ; 435 693 ; 4352523 ; 4353201 ; 514-2 ; 536 221 ; 536 231 ; 536 232 ; 536 234 ; 536 237 ;
Abstract
The invention features a polypeptide consisting of amino acids 379-535 of diphtheria toxin, and portions thereof. This region, shown by X-ray crystallographic analysis to comprise the receptor binding domain of diphtheria toxin, is used as an immunogen and clinical therapeutic against diphtheria.