The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 1998

Filed:

Apr. 26, 1996
Applicant:
Inventors:

Mark S Kaminski, Ann Arbor, MI (US);

Gregory M Butchko, Miami Lakes, FL (US);

Stephan D Glenn, Davis, FL (US);

Richard L Wahl, Ann Arbor, MI (US);

Assignees:

Coulter Pharmaceutical, Inc., Palo Alto, CA (US);

Regents of the University of Michigan, Ann Arbor, MI (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ;
U.S. Cl.
CPC ...
424-149 ; 4241441 ; 4241301 ; 4241791 ; 424-153 ; 5303877 ; 5303881 ; 5303913 ;
Abstract

Methods for the treatment of lymphoma by administration of a B cell-specific antibody are described. The invention encompasses providing to a patient both unlabeled antibodies and antibodies labeled with a radioisotope. A principal advantage of the method is that tumor responses can be obtained in a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy.


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