The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 1998
Filed:
Sep. 21, 1995
Applicant:
Inventors:
Joseph J Hlavka, Tuxedo Park, NY (US);
Matthew R Pincus, Brooklyn, NY (US);
John Fowler Noble, Pomona, NY (US);
Henry Baxter Abajian, Hillsdale, NJ (US);
Andrew S Kende, Pittsford, NY (US);
Assignee:
Innapharma, Inc., Upper Saddle River, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ;
U.S. Cl.
CPC ...
514-9 ; 514 11 ; 514 14 ; 514 15 ; 514 16 ; 514 17 ; 514 18 ; 530317 ; 530326 ; 530327 ; 530328 ; 530329 ; 530330 ; 530331 ;
Abstract
The present invention provides peptides and cyclized peptides which inhibit the oncogenic and/or transforming activity of the p21 ras protein, pharmaceutical compositions containing at least one of the ras-inhibiting peptides, cyclized peptides and peptidomimetics, and methods for inhibiting the ras-mediated oncogenic and/or transformation process in mammalian cells or tissues.