The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 1998
Filed:
May. 01, 1995
Applicant:
Inventors:
Robert Craig Hockney, Cheshire, GB;
Bhuphendra Vallabh Kara, Cheshire, GB;
Assignee:
Imperial Chemical Industries PLC, London, GB;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ;
U.S. Cl.
CPC ...
435 695 ; 435 691 ;
Abstract
Processes for preparing polypeptides, such as G-CSF or analogues thereof, in which fermentation is carried out in the presence of at least one amino acid which is present in an amount sufficient to give improved accumulation of the polypeptide. The amino acid may be threonine and/or leucine which is present in the growth medium at a concentration of, for example, about 1.25 to 5 g/l.