The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 1998
Filed:
Feb. 22, 1994
Applicant:
Inventors:
June Rothman Scott, Atlanta, GA (US);
Vincent Angelo Fischetti, West Hempstead, NY (US);
Assignees:
The Rockefeller University, New York, NY (US);
Emery University, Atlanta, GA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C12P / ; C07K / ;
U.S. Cl.
CPC ...
4242441 ; 435 693 ; 4352523 ; 530350 ;
Abstract
Methods and compositions are provided for the cloning and expression of Streptococcus pyogenes M protein genes, and, in particular, types 5, 6 and 24 gene in single-cell host organisms. The streptococcal M protein produced by the recombinant DNA techniques described herein may be formulated for use as immunogens in vaccines to protect against S. pyogenes infections. The gene for the M protein may further be employed as a molecular probe for the accurate identification of streptococci in infected body tissues and fluids.