The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 1998
Filed:
Mar. 28, 1997
Bruce A Pearlman, Kalamazoo, MI (US);
William R Perrault, Kalamazoo, MI (US);
Michael R Barbachyn, Kalamazoo, MI (US);
Peter R Manninen, Portage, MI (US);
Dana S Toops, Kalamazoo, MI (US);
David J Houser, Portage, MI (US);
Thomas J Fleck, Scotts, MI (US);
Pharmacia & Upjohn Company, Kalamazoo, MI (US);
Abstract
The present invention includes processes for producing 5-hydroxymethyl substituted oxazolidinone alcohols (III) from carbamates (IIA) or a trifluoroacetamide (IIB) using a dihydroxy compound (I) or glycidol (IV) starting material and for the transformation of the hydroxymethyl substituted oxazolidinone alcohols (III) to the corresponding amino compounds, 5-aminomethyl substituted oxazolidinone amines (VII) which are acylated to form commercially useful antibacterial 5-acylamidomethyl substituted oxazolidinone (VIII).