The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 1998

Filed:

Aug. 05, 1996
Applicant:
Inventors:

John H Dodd, Pittstown, NJ (US);

Lisa A Dixon, Somerville, NJ (US);

James L Bullington, Hamilton Square, NJ (US);

Charles F Schwender, Califon, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07C / ;
U.S. Cl.
CPC ...
514765 ; 514381 ; 514546 ; 514625 ; 514656 ; 514718 ; 514717 ; 514721 ; 514729 ; 514753 ; 514680 ; 548251 ; 560129 ; 560190 ; 562-8 ; 564221 ; 564222 ; 564426 ; 568326 ; 568632 ; 568633 ; 568808 ; 574123 ; 574183 ; 585 26 ; 585 27 ;
Abstract

Tetracyclic compounds having the following structure are described: ##STR1## wherein R.sub.1 -R.sub.10 are as defined. The tetracyclic compounds are capable of potent effects on steroid sensitive tissues and have demonstrated increased uterine weight, antiovulatory effects and potent steroid receptor binding. The compounds have therapeutic utility in reproductive applications such as fertility control, labor induction, ovulation induction and spermatogenesis. Methods for preparing the tetracyclic compounds from substituted indanones are also described.


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