The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 1998

Filed:

Jun. 27, 1997
Applicant:
Inventors:

Frederick Earl Boyer, Jr, Canton Township, MI (US);

John Michael Domagala, Canton, MI (US);

Edmund Lee Ellsworth, Brighton, MI (US);

Christopher Andrew Gajda, Ann Arbor, MI (US);

Susan Elizabeth Hagen, Canton Township, MI (US);

Harriet Wall Hamilton, Chelsea, MI (US);

Elizabeth Ann Lunney, Ann Arbor, MI (US);

Larry James Markoski, Ypsilanti, MI (US);

Josyula Venkata Vara Prasad, Ann Arbor, MI (US);

Bradley Dean Tait, Canton, MI (US);

Assignee:

Warner-Lambert Company, Morris Plains, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
514460 ; 514252 ; 514397 ; 514459 ; 549214 ; 549292 ; 5483111 ; 544374 ;
Abstract

This invention pertains to improved antiviral activity of 6,6-disubstituted-5,6-dihydropyran-2-ones caused by judicious placement of certain polar substituents at the 3 and/or 6 positions. The same substituents which enhance the cellular activity also diminish cytotoxicity further enhancing the desirable properties of these agents as antivirals.


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