The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 1998

Filed:

Jul. 02, 1996
Applicant:
Inventors:

Gloria Anne Breault, Congleton, GB;

John Oldfield, Wilmslow, GB;

Howard Tucker, Macclesfield, GB;

Peter Warner, Macclesfield, GB;

Assignee:

Zeneca Limited, London, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514247 ; 514255 ; 514269 ; 514275 ; 514256 ; 514350 ; 514352 ; 514354 ; 514355 ; 514356 ; 514438 ; 514445 ; 514447 ; 514461 ; 514471 ; 514474 ; 514535 ; 514543 ; 514544 ; 514617 ; 514618 ; 514622 ; 514619 ; 514620 ; 514361 ; 514365 ; 514369 ; 514370 ; 514374 ; 514376 ; 514398 ; 514399 ; 514400 ; 514407 ; 514403 ; 562490 ; 562452 ; 562433 ; 562473 ; 562495 ; 560-8 ; 560 17 ; 560 19 ; 560 43 ; 560104 ; 560435 ; 560183 ; 564162 ; 564164 ; 564182 ; 564184 ; 544406 ; 544407 ; 544335 ; 544318 ; 544319 ; 544329 ; 544332 ; 544224 ; 544238 ; 544239 ; 546299 ; 546309 ; 546310 ; 546315 ; 546316 ; 546322 ; 549 64 ; 549 69 ; 549 70 ; 549 71 ; 549 72 ; 549479 ; 549480 ; 549484 ; 549486 ; 549487 ; 548127 ; 548128 ; 548129 ; 548146 ; 548188 ; 548194 ; 548200 ; 548201 ; 548215 ; 548228 ; 548230 ; 548233 ; 548236 ; 548243 ; 548245 ; 548246 ; 548248 ; 5483164 ; 5483215 ; 5483225 ; 5483231 ; 5482694 ; 5482697 ; 5482725 ; 5482741 ; 548556 ; 548557 ; 548562 ;
Abstract

This invention relates to substituted and unsubstituted ���(aryl- and heteroaryl-) alkyl-, alkyloxy-, alkylthio-, oxo-, thio-, and alkylamino!- heteroaryl and aryl!- alkylamino-, aminoalkyl-, alkyloxy-, and alkylthio!- aryl and heteroaryl compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof, which are useful as antagonists of the pain enhancing effects of E-type prostaglandins, to processes for the preparation of such compounds, to pharmaceutical compositions comprising such compounds, and to methods for treating pain comprising the administration of such compounds.


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