The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 1998
Filed:
Jan. 31, 1991
Applicant:
Inventor:
Paul Hutsell Maupin, San Diego, CA (US);
Assignee:
Xytronyx, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12Q / ; C12Q / ; G01N / ;
U.S. Cl.
CPC ...
435 15 ; 435 16 ; 435-4 ; 435975 ; 435-74 ; 435184 ; 436 63 ;
Abstract
Novel assay kits and methods are described for the detection and determination of the severity of disease conditions associated with elevated levels of aspartate aminotransferase (AST). The AST levels are determined by reaction of the AST with cysteine sulfinic acid (CSA) substrate in the presence of a sulfite-reactive dye compound that is substantially nonreactive with AST or CSA, such as a triarylmethine dye. Sulfite ion formed by the reaction of AST with CSA causes a calorimetric indication of AST that can be related to a predetermined stage of disease.