The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 1998

Filed:

May. 24, 1995
Applicant:
Inventors:

Keith E Dionne, Rehoboth, MA (US);

Dwaine F Emerich, Providence, RI (US);

Diane Hoffman, Cambridge, MA (US);

Paul R Sanberg, Spring Hill, FL (US);

Lisa Christenson, New Haven, CT (US);

Orion D Hegre, Green Valley, AZ (US);

David W Sharp, St. Louis, MO (US);

Paul E Lacy, Webster Grove, MO (US);

Patrick Aebischer, Lutry, CH;

Alfred V Vasconcellos, Cranston, RI (US);

Michael J Lysaght, Greenwich, RI (US);

Frank T Gentile, Warwich, RI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
424422 ; 424423 ; 424424 ; 424426 ; 424427 ; 424430 ; 424434 ; 424437 ; 424489 ; 424490 ;
Abstract

A method of forming an implantable and retrievable immunoisolatory vehicle is disclosed, the method comprising the steps of first forming a jacket of biocompatible thermoplastic or hydrogel, and then loading the jacket with a core comprising a volume of at least 1 .mu.l and at least 10.sup.4 cells capable of secreting a biocompatible matrix comprising a hydrogel or extracellular matrix, said jacket having a molecular weight cutoff permitting passage of molecules thereacross to provide said biologically active product or said function.


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