The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 1998
Filed:
Oct. 30, 1992
Applicant:
Inventors:
Michelle Letarte, Toronto, CA;
Joan Massague, New York, NY (US);
Carmelo Bernabeu, Madrid, ES;
Sela Cheifetz, Concord, CA;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; A61K / ; C12N / ;
U.S. Cl.
CPC ...
514-2 ; 514-8 ; 530350 ; 530395 ;
Abstract
This invention provides a novel purified TGF-.beta.-binding glycoprotein, endoglin, an isolated nucleic acid molecule that encodes an amino acid sequence corresponding to the TGF-.beta.-binding glycoprotein, soluble endoglin-derived polypeptide, and fragments thereof. A pharmaceutical composition which comprises the endoglin-derived polypeptide purified by applicants or produced by applicants' recombinant methods and a pharmaceutically acceptable carrier is further provided as well as methods of treating patients which comprise administering to the patient the pharmaceutical composition of this invention.