The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 1998
Filed:
Nov. 27, 1996
Applicant:
Inventors:
Nobufusa Serizawa, Tokyo, JP;
Ichiro Watanabe, Tokyo, JP;
Assignee:
Sankto Company, Limited, Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C07H / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 691 ; 435189 ; 43525235 ; 4353201 ; 536 231 ; 536 234 ; 536 237 ; 536 241 ;
Abstract
A 1 kbp length of the 5'-noncoding region of the gene encoding cytochrome P-450.sub.sca-2 in the actinomycete Streptomyces carbophilus has transcription promoter activity which is substrate inducible. When the 1 kbp region is shortened, transcription activity becomes constitutive and the shortened promoters can be used advantageously in expression systems, especially those expressing P-450.sub.sca-2 in the presence of ML-236B to produce pravastatin sodium.