The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 1998
Filed:
Mar. 31, 1997
Applicant:
Inventor:
Fred I Chasalow, San Carlos, CA (US);
Assignee:
Amur Pharmacuticals, Inc., Belmont, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424-177 ; 514177 ; 514420 ; 514422 ; 514533 ;
Abstract
Disclosed herein are methods for increasing the aqueous solubility and bio-availability of bioactive agents having a free carboxyl group by conjugating the agent to one or more amino alcohol phosphocholine moieties selected from the group consisting of sphingosylphosphocholine, 2-aminoglycerol phosphocholine, serine-phosphocholine, threonine phosphocholine, tyrosine-phosphocholine, aminoethanol-phosphocholine or hydroxyproline-phosphocholine. Also disclosed herein are pharmaceutical formulations comprising the agents produced by the method.